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What Is Tetrahydrofuran?

Views: 279     Author: Vickey     Publish Time: 2023-06-28      Origin: Site


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What Is Tetrahydrofuran?

The solvent tetrahydrofuran, sometimes known as THF, is a white liquid with a mild polarity. It is regarded as an oxygen-containing heterocyclic molecule. Since this oxygen atom may form hydrogen bonds, the molecule is very water-soluble. Many organic substances can be dissolved by THF. Additionally, it is readily evaporative during chemical reactions and has a low boiling point. THF may polymerize into a substance called polytetramethylene ether glycol (PTMEG), which is used to create elastic textiles, when exposed to strong acids.

Tetrahydrofuran is utilized in commercial goods like varnishes as well as chemical synthesis in the lab. Despite being generally harmless, it is very flammable. It can produce explosive peroxides when kept in the air, but this can be avoided by adding an inhibitor, such as butylated hydroxytoluene (BHT).

Another stable substance with a low boiling point and great solvency is THF (Tetrahydrofuran). It is frequently used to dissolve and react with different compounds. Additionally, it serves as a raw ingredient in the production of poly(tetramethylene ether) glycol (PTMG), among other compounds.


Surface Coating

Due to the strong solubility of vinyl chloride, even at a high degree of polymerization, THF is used as a solvent for synthetic leather coatings.


Taking advantage of excellent solubility and diffusion properties, THF is used as a solvent for vinyl and epoxy adhesives.

Film Casting

THF is used for vinyl chloride heat-shrinkable film and for desiccant.

Printing Inks

THF is appropriate for printing inks because it can dissolve inorganic substances that are just marginally soluble and evaporate quickly.

Other Uses

Because it can dissolve different resins even at ambient temperature and is miscible with water and the majority of organic solvents, THF is frequently employed as a solvent for specialized resins, such as photosensitive resins. Additionally, it serves as a solvent for Wittig and Grignard processes. It is employed as a solvent for reactions and purification in the manufacture of pharmaceuticals and agricultural products.

Storage and Handling

THF is categorized as a hazardous substance, Class 4, Petroleum No. 1, water-soluble, Hazardous Rank II, under the Japanese Fire Services Act. The storage container must be properly sealed and kept in a well-ventilated area because it is extremely volatile and combustible. Take fire safety measures when handling If THF is exposed to oxygen or air, explosive peroxides will be produced, much like with other ethers. For this reason, dry nitrogen should be used to seal the container.

The skin and mucous membranes of the eyes, nose, and throat are irritated by THF. Long-term exposure to the vapor may result in organic solvent poisoning symptoms such as nausea and dizziness. To prevent vapor concentrations that are too high, provide proper ventilation.When using or handling, always use proper safety equipment such as protective gloves and goggles.

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